Notizen 117 C-13 NMR of Hecubine and Voaphylline, and a Study of Mass Spectral Fragmentation of Hecubine by Linked Scan Measurements
نویسندگان
چکیده
Ervatamia coronaria (Apocynaceae) is a glabrous, evergreen tree commonly grown in the gardens of West Pakistan. A number of indole alkaloids have previously been reported from this plant [1-8]. Two of these, possessing a tetracyclic structure, are voaphylline (I) and hecubine (II). We report here the C-13 NMR of hecubine and voaphylline as well as a study of the mass spectral fragmentation patterns of hecubine which were monitored by examining the metastable ion transitions as determined by linked scan measurements. Hecubine showed following peaks in its mass spectrum: 310 (M+ 66%), 281 (11%), 226 (39%), 184 (17%), 170 (75%), 166 (8.3%), 158 (72%), 152 (12%), 144 (28%), 140 (100%,), 138 (10%), 124 (9%).
منابع مشابه
A hybrid density functional theory (DFT) and ab initio study of α-Acyloxycarboxamides Derived from Indane-1, 2, 3-trione
α-acyloxycarboxamides are synthesized from three component Passerini reaction between indane-1,2,3-trione, isocyanides, and thiophenecarboxylic acids in quantitative yields. The structures of the final products were confirmed by IR, 1H and 13C NMR spectroscopy, mass spectrometry, and elemental analysis. The B3LYP/HF calculations for computation of 1H an...
متن کاملSynthesis and spectral characterization of naphthyldihydrazones derived from some 1,3- dicarbonyl compounds and their Ni(II), Cu(II) and Zn(II) complexes
The coupling of tetrazotised 1,8-diaminonaphthalene with 1,3-dicarbonyl compounds [acetylacetone,methylacetoacetate and acetoacetanilide] yielded a new series of tetradentate ligand systems. Analytical, IR,1H NMR and mass spectral data indicate that the compounds exist in the intramolecularly hydrogen bondeddihydrazone form. Dibasic tetradentate N2O2 coordination of these compounds in their [ML...
متن کاملPreparation and NMR, Mass and Mössbauer Studies of Di-and Triorganotin (IV) Derivatives of 3-(2-Furanyl)-2- Propenoic Acid
3-(2-Furanyl)-2-propenoic acid has been used to prepare a new series of organotin complexes of general formula R3SnL (R=Me, Et, n-Bu, Ph and Cy) and R2SnL2 (R=Me and n-Bu). These complexes have been characterized by elemental analyses, IR, 1H-NMR, MASS and Mössbaure spectroscopy.
متن کاملCytotoxic and anticancer studies of an oxygen and nitrogen donor novel Schiff base ligand and its copper (II) complex
A selected solid complex of the Schiff base ligand derived from Glutaric anhydride with Cu(II) ion was synthesized and characterized by FT-IR, Electronic, ESR Spectral Analyses, Magnetic susceptibility and Molar Conductance Measurements. The disappearance of ν(O-H) hydroxyl band of the phenolic and the lowering shift of the stretching frequency of the ν(CH=N) azomethine band in the ligand after...
متن کاملTheoretical study of structure spectral properties of Tacrine as Alzheimer drug
Tacrine (9-amino-1,2,3,4-tetrahydroacridine) as a reversible inhibitor of acetylcholinesterase (AChE),was the first drug for the symptomatic treatment of Alzheimer’s disease (AD). NMR structuredetermination still presents some considerable challenges: the method is limited to systems ofrelatively small molecular mass, data collection times are long, data analysis remains a lengthyprocedure, and...
متن کامل